The revolutionary ibuprofen replacement – Breakthrough Labz releases a shocking new joint formula
Once you see this formula and its doses…well…just make sure you’re sitting down
“We at Breakthrough Labz wanted a joint product that you could take daily without worry, that gave the relief that ibuprofen does, the anti-inflammatory effects of Tumeric Curcumin, and the cartilage repair of Cissus Quadrangularis. The result was the development of Breakthrough RELIEF, confidently the strongest joint supplement on the market. We’re proud to finally have it ready and available to the public.”
Once again, Breakthrough Labz took multiple products that have successfully helped hundreds of customers and combined them into one incredible product. After spending a few years combining formulas and collecting customer feedback, the ultimate joint recovery and relief product has been created. Breakthrough RELIEF contains the most effective anti-inflammation, recovery, and disease prevention ingredients to help with the healing and comfort of your vital joints and tendons.
Having maxed out the doses in RELIEF, the serving size is 6 capsules. Each bottle of RELIEF contains 180 capsules, so users have the flexibility to dose it to their needs. You can assess your tolerance and start with ½ serving per day for the first few days, stepping it up to a full 6-capsule serving as you please. It’s best taken by separating the doses 4-8 hours apart. For example, one may want to start with 2 capsules twice per day for the first week and may increase the doses once their tolerance and needs are assessed… up to 2 capsules three times per day OR 3 capsules twice per day.
For maximum joint comfort, take Breakthrough OMEGA alongside Breakthrough RELIEF.
What’s in this All-in-One Joint Support?
Per serving (6 caps), 30 servings:
- 1500mg Cissus Quadrangularis
- 1250mg Glucosamine Sulfate
- 1000mg Turmeric Curcumin
- 800mg Sodium Chondroitin Sulfate
- 100mg Boswellia Seratta
- 30mg White Willow Bark
- 5mg Piperine Black Pepper
Add Enteric Coated Caps and BAM! The most powerful all-in-one joint supplement on the market today.
Highlights of Breakthrough RELIEF:
- 1.All-in-One Joint Recovery and Comfort Formula
- 2.Releases joint enzymes
- 3.Reduces joint pain and supports sensitive joint cartilage
- 4.Promotes joint mobility
- 5.Defends against free radicals with plant-based antioxidants
- 6.Slows down arthritis and the breakdown of cartilage
- 7.Enhances joint and bone healing
- 8.Uses Enteric Coated Capsules for maximum absorption and effectiveness
- 9.No Proprietary Blend – this incredible formula has nothing to hide
Looking at the ingredients…
Ability to heal broken bones, reduce joint pain, and balance blood sugar
Cissus Quadrangularis is a perennial plant that belongs to the grape family. Within Ayurvedic medicine, Cissus Quadrangularis has been used to heal injured tendons, bones, and ligaments.
Within Siddha medicine, it’s viewed as a natural pain killer and tonic, as well as a healer from broken bones. Today, it’s currently used by athletes as well, based on exercise-related joint pain. When studying rats, it appeared to be an effective painkiller.
Although few human studies have been conducted, one study focused on athletes and yielding positive effects. Those who took Cissus Quadrangularis experienced a reduction in joint pain by a third. This could be promising for athletes, as most joint health supplements do not report much athlete-based evidence, as most research is conducted on people with osteoarthritis.
Cissus Quadrangularis is best known for its potential ability to heal broken bones faster than normal. When studying dogs, it was proven that Cissus Quadrangularis offered healing effects. One group of dogs were given Cissus Quadrangularis while the other were given a placebo. After 21 days, those who were given a placebo had not healed, yet those who ingested Cissus Quadrangularis had healed completely.
A similar study was conducted in rats, as those who were given Cissus Quadrangularis healed 50 percent faster. While studying these effects, researchers believe that Cissus Quadrangularis may help increase the uptake of calcium. This makes sense, as calcium is one of the key nutrients that’s required for optimal bone strength. There’s also evidence suggesting that Cissus Quadrangularis taken every day could reduce the risk of fracturing a bone by up to 40 percent.
There’s also some evidence supporting the notion that Cissus Quadrangularis may contribute to weight-loss. When combined with an exercise and balanced diet plan, Cissus Quadrangularis could promote a reduction in weight and burn fat. Within one study, a group was given Cissus Quadrangularis, while another group was given a placebo.
Those who took Cissus Quadrangularis lost 187 percent more weight in comparison to the placebo group. Researchers believe that this supplement can help burn fat, reduce appetite, and increase lean muscle mass. Since lean muscle mass supports a higher metabolism, you can burn more calories, even at rest.
In another study, three groups were studied. The first was given a placebo, the second was given cissus quadrangularis and the third was given Cissus Quadrangularis while following a diet plan. After eight weeks, it was found that both groups taking Cissus Quadrangularis lost a significant amount of weight. They also were able to reduce their blood pressure, cholesterol, and triglycerides, while better balancing their blood sugar.
Speaking of blood sugar, cissus quadrangularis could help reduce the risk of diabetes, particularly type II. Over the past few years, the number of individuals with type II diabetes has skyrocketed. This has a lot to do with our current lifestyles and poor diet choices. Since cissus quadrangularis helps control one’s blood sugar, it can also reduce one’s risk of becoming pre-diabetic and then developing type II diabetes. Type II diabetes is highly correlated with obesity so cissus quadrangularis’s weight-loss effects would also be beneficial.
Cissus quadrangularis is also packed with vitamin C, making it a natural antioxidant. In turn, this helps fight inflammation, reducing swelling, pain, and other associated health complications. Many health experts in the field have compared cissus quadrangularis to the same pain-relieving effects as aspirin.
[Sourced from Nootropicsinfo.com]
Slows the progression of osteoarthritis and eases the pain as effectively as ibuprofen
Glucosamine sulfate is a natural sugar found in and around the fluid and tissues that cushion your joints. This tissue is called cartilage. Glucosamine is also found in the hard covering of shellfish. Glucosamine sulfate supplements are often made using shellfish. The substance can also be made in a laboratory.
Glucosamine sulfate is a widely used supplement that may help ease pain in people with osteoarthritis. Osteoarthritis happens when cartilage breaks down. This can cause joint pain. Millions of people in the U.S. have osteoarthritis.
Scientists have been studying glucosamine sulfate alone, and together with another supplement called chondroitin, for many years. Research results have been conflicting.
Some studies show the supplement reduces knee pain in people with moderate-to-severe osteoarthritis.
The supplement seems to reduce pain as much as ibuprofen. But it doesn't work as fast. It can take four to eight weeks for glucosamine sulfate to ease pain.
Some studies show that glucosamine sulfate may also work for: Osteoarthritis of the hip or spine; and Arthritis of the temporomandibular joint (TMJ) in the jaw.
A study in men also suggests that glucosamine sulfate may help a person bend and flex the knee better after a sudden knee injury. Glucosamine may also slow the progression of osteoarthritis.
Optimal doses of glucosamine sulfate have not been established. Supplement ingredients and quality may vary widely from maker to maker. This makes it hard to establish a standard dose.
The dose used in many studies to treat knee osteoarthritis was 500 milligrams, taken three times a day.
There are different forms of glucosamine. Check the supplement's ingredients. Some may contain glucosamine sulfate. Other supplements may have glucosamine hydrochloride or another type. Most studies have used glucosamine sulfate.
Glucosamine is sometimes found in skin creams used to treat arthritis pain. There is no proof that glucosamine can move through your skin. Scientists think the pain relief may be due to other ingredients in the cream.
Studies done in a laboratory dish hint that glucosamine sulfate may help fight HIV, the virus that causes AIDS. Much more comprehensive research is needed before scientists can say whether or not this supplement could be helpful for those with the virus.
[Sourced from WebMD]
Powerful antioxidant that reduces free radicals that damage your cells and DNA
Turmeric is a spice derived from the rhizome and root of the Curcuma longa plant, which is native to India and Indonesia. People have consumed turmeric for its flavor and health-promoting properties for 4,000 years. Curcumin is the major active ingredient responsible for turmeric’s medicinal properties. Using turmeric as a spice is a healthful practice but taking its derivative curcumin as an herbal supplement will produce a more profound medicinal effect. As with all herbal supplements, talk to your health-care practitioner before supplementing with curcumin.
Antioxidant and Anti-inflammatory Benefits: Curcumin, the active ingredient in turmeric, is a powerful antioxidant. It helps to reduce and neutralize free radicals, which damage and destroy your cells and DNA. Curcumin also reduces two inflammation-promoting enzymes in your body and is therefore an effective anti-inflammatory agent. Due to curcumin's ability to reduce inflammation, the University of Maryland Medical Center, or UMMC, states that curcumin supplements may help to relieve symptoms of osteoarthritis, a condition characterized by inflammation, pain and stiffness in the joints.
Intestinal and Bowel Health: Curcumin stimulates the gallbladder to produce bile, and consuming the spice turmeric regularly, or supplementing with its active ingredient curcumin, may help to improve digestion, reduce bloating and gas and treat digestive disorders. In addition, curcumin supplements combined with conventional medical treatment may help treat bowel disorders such as ulcerative colitis.
Cardiovascular Health: Curcumin is purported to help prevent cardiovascular disease and may be particularly beneficial for the prevention of atherosclerosis, a condition characterized by a hardening and narrowing of the arteries. UMMC states that curcumin has been found to lower total cholesterol and LDL cholesterol levels and to prevent the blood from clotting. The research on curcumin supplements for cardiovascular disease is preliminary, however, and has not yet been conducted on humans.
Cancer: Consuming turmeric regularly or taking a curcumin supplement may help to prevent and treat cancer. Curcumin appears to block the blood supply to cancerous tumors, and consequently to suppress the growth and replication of tumor cells. According to "Principles & Practice of Pediatric Oncology," extensive research has indicated that curcumin can prevent cancer in animals. In addition, high intakes of turmeric have reduced the rate of colorectal, lung and prostate cancer in humans.
Additional Uses: Taking a curcumin supplement may help prevent and treat bacterial and viral infections. Curcumin supplements are also used to treat liver problems and skin disease, lower blood sugar levels in diabetics and reduce kidney stones. In addition, curcumin may help to treat an inflammatory eye condition known as uveitis. More research needs to be done confirm the efficacy of curcumin supplements for these purposes, however.
[Sourced from Livestrong.com]
Sodium Chondroitin Sulfate
Used to slow down the breakdown of cartilage caused by osteoarthritis
Chondroitin sulfate is a chemical that is normally found in cartilage around joints in the body. Chondroitin sulfate is usually manufactured from animal sources, such as shark and cow cartilage.
Chondroitin sulfate is used for osteoarthritis. It is often used in combination with other ingredients, including manganese ascorbate, glucosamine sulfate, glucosamine hydrochloride, or N-acetyl glucosamine.
In osteoarthritis, the cartilage in the joints breaks down. Taking chondroitin sulfate, one of the building blocks of cartilage, might slow this breakdown.
Chondroitin sulfate is also taken by mouth for HIV/AIDS, heart disease, heart attack, weak bones (osteoporosis), joint pain caused by drugs used to treat breast cancer, acid reflux, high cholesterol, muscle soreness after exercise, a bladder condition called interstitial cystitis, a bone disease called Kashin-Beck disease, and itchy and scaly skin (psoriasis). Chondroitin sulfate is also used in a complex with iron for treating iron-deficiency anemia.
Chondroitin sulfate is available as an eye drop for dry eyes. In addition, it is used during cataract surgery, and as a solution for preserving corneas used for transplants. It is approved by the FDA for these uses.
Some people with osteoarthritis use ointments or skin creams for pain that contain chondroitin sulfate, in combination with glucosamine sulfate, shark cartilage, and camphor.
Some people also inject chondroitin sulfate into the muscles for osteoarthritis.
Some people insert chondroitin sulfate into the bladder for urinary tract infections (UTIs), bladder conditions, or loss of control of the bladder.
[Sourced from WebMD]
Anti-cancer herb that prevents cartilage breakdown and is an effective anti-inflammatory
Boswellia Serrata is a gum resin extracted from a tree, which is sometimes burnt (the entire species of Boswellia is commonly known as Frankinsence) as an aromatic or otherwise administered as medicine. It has most usage for medicine in Ayurvedic medicine, some reading into Traditional Chinese Medicine, and its usage extends to the Middle East and other tropical regions.
Boswellia Serrata, via its active boswellic acids, appears to be a novel inhibitory of a pro-inflammatory enzyme called 5-Lipoxygenase and may possess other anti-inflammatory effects (such as nF-kB inhibition, which are not as novel). These anti-inflammatory effects have been investigated for their benefits in osteoarthritis (OA), and it appears that oral Boswellia supplements can suppress pain and immobility associated with OA quite significantly with the effects taking as little as a week to occur. The studies are well conducted but funded by the producers of the tested supplements. There are limited non-funded interventions with Boswellic for this claim, but they seem to agree with the battery of funded study in effect size.
Remarkably, Boswellia appears to be quite anti-cancer that appears to be more anti-proliferative rather than apoptotic (the latter meaning to induce regulated cell death) since it is a potent inhibitor of angiogenesis and cell invasiveness. There is not a large battery of studies on these claims, but preliminary mouse and rat evidence where the rodents are injected with tumors suggest that Boswellia can potently suppress tumor growth (Pancreatic, Colorectal) and in some cases actually outright prevent tumor growth (Prostatic, Glioma). Boswellia appears to be a very promising anti-cancer herb due to the potency it exhibits in animals, with one study noting this after oral administration (100mg/kg of the main boswellic acid in animals). The potency has been replicated in other cancer cell lines in vitro (including breast, cervical, myeloma and leukemia) but these cancers do not yet have animal interventions yet.
[Sourced from Examine.com]
Boswellia, also known as Indian frankincense, is an herbal extract taken from the Boswellia serrata tree.
Resin made from boswellia extract has been used for centuries in Asian and African folk medicine. It’s believed to treat chronic inflammatory illnesses as well as a number of other health conditions. Boswellia is available as a resin, pill, or cream.
Studies show that boswellia may reduce inflammation and may be useful in treating the following conditions: osteoarthritis (OA), rheumatoid arthritis (RA), asthma, and inflammatory bowel disease (IBD).
Because boswellia is an effective anti-inflammatory, it can be an effective painkiller and may prevent the loss of cartilage. Some studies have found that it may even be useful in treating certain cancers, such as leukemia and breast cancer.
Some research shows that boswellic acid can prevent the formation of leukotrienes in the body. Leukotrienes are molecules that have been identified as a cause of inflammation. They may trigger asthma symptoms.
Four acids in boswellia resin contribute to the herb’s anti-inflammatory properties. These acids inhibit 5-lipoxygenase (5-LO), an enzyme that produces leukotriene. Acetyl-11-keto-β-boswellic acid (AKBA) is thought to be the most powerful of the four boswellic acids. However, other research suggests other boswellic acids are responsible for the herb’s anti-inflammatory properties.
Boswellia products are generally rated on their concentration of boswellic acids.
Many studies of boswellia’s effect on OA have found that it’s effective in treating OA pain and inflammation.
One 2003 study published in the journalPhytomedicine found that all 30 people with OA knee pain who received boswellia reported a decrease in knee pain. They also reported an increase in knee flexion and how far they could walk.
Newer studies support the continued use of boswellia for OA.
Another study, funded by a boswellia production company, found that increasing the dosage of enriched boswellia extract led to an increase in physical ability. OA knee pain decreased after 90 days with the boswellia product, compared to a lesser dosage and placebo. It also helped reduce the levels of a cartilage-degrading enzyme.
Studies on the usefulness of boswellia in RA treatment have shown mixed results. An older study published in the Journal of Rheumatology found that boswellia helps to reduce RA joint swelling. Some research suggests that boswellia may interfere with the autoimmune process, which would make it an effective therapy for RA. Further research supports the effective anti-inflammatory and immune-balancing properties.
Due to the herb’s anti-inflammatory properties, boswellia may be effective in treating inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis (UC).
A 2001 study compared H15, a special boswellia extract, to the anti-inflammatory prescription drug mesalamine (Apriso, Asacol HD). It showed that the boswellia extract may be effective in treating Crohn’s disease.
Several studies found the herb could be effective in treating UC as well. We’re just beginning to understand how the anti-inflammatory and immune-balancing effects of boswellia can improve the health of an inflamed bowel.
Boswellia can play a role in reducing leukotrienes, which causes bronchial muscles to contract. A 1998 study of the herb’s effect on bronchial asthma found that people who took boswellia experienced decreased asthma symptoms and indicators. This shows the herb could play an important role in treating bronchial asthma. Research continues and has shown the positive immune-balancing properties of boswellia can help the overreaction to environmental allergens that happens in asthma.
Boswellic acids act in a number of ways that may inhibit cancer growth. Boswellic acids have been shown to prevent certain enzymes from negatively affecting DNA.
Studies have also found that boswellia may fight advanced breast cancer cells, and it may limit the spread of malignant leukemia and brain tumor cells. Another study showed boswellic acids to be effective in suppressing the invasion of pancreatic cancer cells. Studies continue and the anti-cancer activity of boswellia is becoming better understood.
[Sourced from Healthline.com]
White Willow Bark
Similar to aspirin, helping with inflammation, pain, headaches, and arthritis
Willow bark is the bark from several varieties of the willow tree, including white willow or European willow, black willow or pussy willow, crack willow, purple willow, and others. The bark is used to make medicine.
Willow bark acts a lot like aspirin, so it is used for pain, including headache, muscle pain, menstrual cramps, rheumatoid arthritis (RA), osteoarthritis, gout, and a disease of the spine called ankylosing spondylitis.
Willow bark’s pain-relieving potential has been recognized throughout history. Willow bark was commonly used during the time of Hippocrates, when people were advised to chew on the bark to relieve pain and fever.
Willow bark is also used for fever, the common cold, flu, and weight loss.
Willow bark contains a chemical called salicin that is like aspirin.
Treating lower back pain. Willow bark seems to reduce lower back pain. Higher doses seem to be more effective than lower doses. It can take up to a week for significant improvement in symptoms.
[Sourced from WebMD]
Most willows are found in temperate and arctic zones. They are geographically distributed in all continents except Antarctica and Australia. Willows include small trees, shrubs, and groundcovers, and many species are dioecious with male and female catkins (flowers) on separate plants. The catkins are cylindrical in shape, measuring 6 to 7 cm in length. The male flowers are yellow, and the female flowers are green. Medicinal willow bark is collected in the early spring from young branches (2 to 3 years of age).
The medicinal use of willow dates back 6,000 years. Ancient civilizations used willow tree extracts to treat pain, inflammation, and musculoskeletal conditions.
Willow bark can be an effective pain reliever if the salicylate content is adequate. Anticancer, antioxidant, and anti-inflammatory activity has been documented in limited trials. Clinical trials have shown that willow has moderate efficacy in treating lower back pain but very little efficacy in treating arthritic conditions.
[Sourced from Drugs.com]
Piperine Black Pepper
An effective ‘bioenhancer’, helping with the absorption of Curcumin and other vitamins and supplements
Black Pepper is a spice commonly used in many areas of the world for flavor. Through its active component Piperine, Black Pepper is able to modify supplement and drug metabolism.
A process in the liver called glucuronidation, which attaches a molecule (glucuronide) to drugs to signal for their urinary excretion, is inhibited with piperine. This process prevents excessive levels of drugs and supplements in the body, but sometimes inhibits all uptake and renders some supplements useless. In the scenario of piperine ingestion, excretion of supplements is hindered, and certain drugs and supplements can bypass this regulatory stage (as not all are subject to it).
This is good in some cases, as Piperine is required to give curcumin to the extremities rather than it is getting consumed by glucuronidation in the liver. However, in some other cases it can lead to elevated levels of certain drugs in the blood. Again, elevated could be good or bad depending on context; regardless, caution should be taken when approaching this compound.
[Sourced from Examine.com]
Piperine, also known by its trademarked name, BioPerine, is an extract derived from black pepper, Piper Nigrum L, and long pepper, Piper longum L. Piperine is what gives peppers their spicy taste. This extract is marketed as a nutritional supplement and has been found to increase the absorption of a variety of nutrients. Though some of the benefits of piperine have yet to be firmly established, it may also have immune-suppressing, tumor-inhibiting and antidepressant effects. While piperine is probably safe to use, some concerns have been raised regarding its potentially dangerous, enhancing effect on certain drugs. As with starting any new treatments, consult your doctor first.
Absorption of Nutrients:The most established effect of piperine is its effect on absorption of nutrients from the intestine. This effect is known as "bioenhancement." According to an article published in the "Journal of Ayruveda and Integrative Medicine" in 2010, piperine has been shown to increase the absorption of vitamin C, selenium, beta-carotene, vitamin A, vitamin B-6 and coenzyme Q. The article goes on to suggest that piperine may be useful for people who suffer from conditions that cause malabsorption of nutrients and people suffering from malnutrition.
Immunomodulator:While the primary immune system functions to eradicate foreign invaders, it can sometimes malfunction. A variety of diseases are caused by a faulty immune reaction. Piperine has been shown to decrease the activity of this inflammatory response. The findings from a study published in the "European Journal of Pharmacology" in 2010 suggest that piperine may decrease the communication of lymphocytes in the immune system, thereby slowing down their action. Piperine has been shown to be beneficial in gout, a disease characterized by a strong immune response against uric acid crystals. A study published in "Inflammation" in 2011 provided evidence that piperine blocked uric acid crystals from forming and that it could be used as a treatment for gout.
Anti-Tumor Effect: Some evidence suggests that piperine may have some anti-cancer properties. A publication in "Clinical Laboratory Science" in 2008, for example, suggests that piperine inhibits the growth of colon cancers cells grown in a lab. The exact mechanisms by which the supplement prevents cancer are unknown, however, and whether this anti-cancer effect is effective outside of the laboratory remains to be proven.
Antidepressant:Piperine may have some antidepressant activity as well, though this has not yet been firmly established. A trial of piperine on rats found that the animals provided evidence that the supplement had antidepressant and cognitive-enhancing effects. These findings were published in "Food and Chemical Toxicology" in 2008. Another study published in "Pharmacology, Biochemistry and Behavior" in 2009 found that piperine increased the neurotransmission of serotonin and dopamine, two chemicals that are often deficient in depressed individuals. Clinical trials testing the supplement are needed to verify whether these benefits transfer to people.
[Sourced from Livestrong.com]
Enteric Capsule Technology: Increased Absorption
This delivery system is known as an enteric coating. This is usually only used with advanced pharmaceutical products.
The enteric coating that we use contains a pH sensitive polymer, which means that it remains intact in the acidic environment of the stomach (pH 1.5 - 3.5), protecting the contents of the tablet.
After passing through the stomach the coating then disintegrates in the small intestine (duodenum) which has an alkaline environment (pH 6.5 - 7.6).
The enteric coating is inert and simply passes through your system without any effect at all. The coating we use is manufactured by Colorcon, a world leader in the development and manufacturing of delayed and immediate release coatings for both pharmaceutical and dietary supplement products. This coating has been thoroughly proven for both safety and efficacy.
Apart from the protection that this system provides for those ingredients in our enteric coated products which could be damaged by stomach acid, it also prevents any irritation of the gastric mucosa in the stomach, which is common with many supplements and drugs.
What are the Benefits of Enteric Coated Capsules?
For some formulations, Enteric Coated Capsules are an ideal choice. This is because they:
Overwhelmingly increase absorption rates - The absorption of high quality supplements can increase from as low as 10% (depending on the individual) to 80% or more.
Will not dissolve in the mouth – Enteric Coated Capsules are perfect for drugs that are acid-activated, as they prevent the drug from activating in the mouth or esophagus.
Will not irritate the stomach – Many drugs, such as aspirin, can irritate the stomach. Because they pass through the stomach intact, Enteric Coated Capsules avoid this problem.
Can preserve enzyme activity – Most tablets break down in the highly acidic environment of the stomach. Unfortunately, depending on the product’s formulation, this acidic environment can also negatively impact the desired enzyme activity. Enteric Coated Capsules protect the enzymes so that they can be absorbed, at their highest activity levels, in the small intestine.
Take longer to dissolve – While most capsules dissolve within 15 minutes, Enteric Coated Capsules do not dissolve until approximately one to two hours after ingestion, when they reach the small intestine. These capsules can therefore provide a “timed-release” affect.
Although enteric coating is a common technology employed with expensive pharmaceutical medications, it is rarely seen in the nutritional supplement industry!
That’s because most supplements are manufactured to a price rather than from a ‘best science’ perspective. Pharmaceuticals always work because they must be based on ‘best science’ since FDA regulations require proof that they work.
The manufacturer of Xtend-Life claims over 80% absorption of ingredients when using enteric coated capsules. An extremely high level for a nutritional or dietary supplement.
Some experts believe that (in non-enteric coated products) the bioavailability of vitamins (i.e. all the contents) is only 10-15% due to damage from gastric juices and enzymes in the stomach. This is a gray area however as there is little conclusive research available dealing with absorption rates since so many individual factors come into play from person to person.